In this issue of cell, two papers report agonistbound cryoem structures of the cannabinoid receptor, cb2, in complex with gi. Medical college, kolhapur, mh, india chemistry of nucleic acids 1. Nucleotides make up the basic units of dna and rna molecules. Find powerpoint presentations and slides using the power of, find free presentations research about nucleic acid ppt. Nucleotide excision repair an overview sciencedirect. Nucleotide excision repair excision repair is a universal repair system that eliminates dna damage by dual incisions bracketing the lesion. This document is highly rated by class 12 students and has been viewed 20618 times. Khan academy is a nonprofit with the mission of providing a free, worldclass education for anyone, anywhere. An introduction is a textbook exclusively focusing on the study of the aspects of nucleotide metabolism. These constituent parts are shown for atp, where the base. Basic nucleic acid structure polymers of nucleotides v held by 5 and 3 sugar phosphate bridges 5.
Though i place them here to give my students 247 access, they may also be used by any teacher or student who can benefit from this resource. Each nucleotide is put together from three building blocks. Deoxyribonucleic acid and ribonucleic acid are nucleotide polymers. Nucleotide excision repair of chemically stabilized analogues of dna interstrand crosslinks produced from oxidized abasic sites. Nucleotides and nucleic acids brief history1 1869 miescher isolated nuclein from soiled bandages 1902 garrod studied rare genetic disorder. Difference between nucleotide and nucleoside structure. This page contains links to the powerpoint presentations that i will be using in class and some that i no longer use. The molecule is composed of two chains of nucleotides the two chains spiral around each other to. The chemistry of abiotic nucleotide synthesis of rna and dna in the context of their prebiotic origins on early earth is a continuing challenge.
An individual nucleotide consists of 3 parts, all of which are covalently bonded together. Dna, nucleotide, basepairing rules, protein we will have a quiz next block on basepairing standards. Biological data molecular biology dna and rna bioinformatics software personalized medicine single nucleotide polymorphism molecular modelling drug docking applications conclusion. All nucleotides consist of a base, a sugar and a phosphate ester.
Nucleic acid structure powerpoint slides learnpick. The circumstantial evidence nucleic acid structure nucleotide structure ribose is a. The nucleotide consists of a phosphate joined to a sugar, known as 2 deoxyribose, to which a base is attached. Amino acids are a group of organic compounds containing two functional groups amino and carboxyl. The slide has some brief introduction to nucleotide chemistry, history, general features of nucleotides, nomenclature, individual properties of bases, classifi slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising.
Nucleic acid chemistry free download as powerpoint presentation. Nucleotides energy rich compounds chemical signals enzyme cofactors nucleic acids dna and rna polymers of nucleotides 3 components nitrogenous base ribose or deoxyribose phosphate bases ribose carbons numbered. Nucleic acid chemistry contents contents 1 mrna messenger rna 5 cap. Nucleic acid chemistry nucleoside nitrogenous base dribose sugar in case of rna and d2deoxyribose in case of dna nucleotides nitrogenous base. How did or how can the nucleotides form and assemble from the small molecule inventories and under conditions that prevailed on early earth 3. Dna and rna can be represented as simple strings of letters, where each letter corresponds to a particular nucleotide, the monomeric component of. Let us begin by considering the nature of the nucleotide, the fundamental building block of dna. View and download powerpoint presentations on nucleotide ppt. A free powerpoint ppt presentation displayed as a flash slide show on id. Chapter 2 structures of nucleic acids dna and rna are both nucleic acids, which are the polymeric acids isolated from the nucleus of cells.
Nucleotide sequence analysis of dna nature new biology. Download ppt for example, the cleavage site of primir497 was moved from c0 to c1 for the mghgrecognition mutants or linker mutants, whereas phosmut cleaved the same site as wt drosha, albeit with a reduced efficiency figure 5 b, top. Nucleic acids are the main informationcarrying molecules of the cell, and, by directing the process of protein synthesis, they determine the inherited characteristics of every living thing. Adenosine monophosphate amp, adenylic acid molecule. Ppt chapter 28 nucleosides, nucleotides, and nucleic. Importantly, beyond providing information that could help distinguish cb2 ligand binding from cb1, these structures support the existence. Inhibitors of human purine synthesis are extremely toxic to tissues, especially to developing structures such as in a fetus, or to cell types that normally replicate rapidly, including those of bone marrow, skin, gastrointestinal gi tract, immune system, or hair. Whether it is an organic or inorganic reaction, it can be explained with free chemistry ppt backgrounds. Ppt nucleotides chemistry powerpoint presentation, free. The technique is extremely useful in current laboratory practice because it provides a rapid and inexpensive access to custommade oligonucleotides of the desired sequence. The phosphate and the sugar have the structures shown in figure 62.
Simplified ppts for easy biochemistry teaching and learning. Powerpoint presentations ppt collection for chemistry. Chapter 2 structures of nucleic acids nucleic acids. Nucleotides characteristics components thursday, february 4, 2016 rajesh chaudhary 6. Nucleotides and nucleic acids chapter 8 lehninger 5th ed. The mechanism of nucleotide excision repair ner of dna ppt what is nucleotide excision repair. Chemistry for biology 3 civil service agriculture 8 civil service botany 22. Phosphorylation of a nucleoside at the 5 carbon of the sugar converts a nucleoside into a nucleotide. The book intends to present the chemistry and metabolism of nucleotides, one of the oldest subjects of biochemistry. Oligonucleotide synthesis is the chemical synthesis of relatively short fragments of nucleic acids with defined chemical structure. We use your linkedin profile and activity data to personalize ads and to show you more relevant ads. Nucleic acid chemistry nucleic acid structure basics. View and download powerpoint presentations on nucleic acid ppt.
Nucleic acid, naturally occurring chemical compound that is capable of being broken down to yield phosphoric acid, sugars, and a mixture of organic bases purines and pyrimidines. Templates include iron, chemistry test tube, entropy, and nuclear medicine among others. Ppt biomacromolecules 2 powerpoint presentation, free download. A nucleotide is an organic molecule made up of a nucleotide base, a fivecarbon sugar ribose or deoxyribose and at least one phosphate group.
The journal of physical chemistry b 2014, 118 46, 1231. Nucleotide structure, nomenclature, derivatives and analogues. Nucleic acids 3 parts of a nucleotide and how they are connected. Ppt nucleic acid chemistry powerpoint presentation. Free chemistry powerpoint templates are made, while keeping in mind students who are required to give clear. The chemical structure of repeating nucleotide subunits in dna and rna. The watsoncrick proposal of dna structure there are 12 summarized proposal by watson and crick of the dna structure as what the xray diffraction data of r. The main difference between nucleotide and nucleoside is that nucleotide is the precursor of both dna and rna whereas nucleoside is the precursor of nucleotide. Find powerpoint presentations and slides using the power of, find free presentations research about nucleotide ppt. The whole art of teaching is only the art of awakening the natural curiosity of young minds. Polymers powerpoint presentation, science, chemistry. Thus better understanding the nucleic acid chemistry would help in gaining a comprehensive knowledge about the various biological processes undertaken by our body at molecular level.
Nucleotide and nucleic acid nomenclature base purines adenine guanine. Biochemistry of dna and rna with full illustration has been incorporated in the power point presentation. An overview of nucleic acid chemistry, structure, and function. Chemical nature of rna thursday, february 4, 2016 24 sugar moiety. Xray diffraction base pairing the double helix powerpoint presentation rna rna secondary structure rna secondary structure dna sequencing dna sequencing. This disconnection approach to synthesis is now a fundamental part of every organic synthesis course. Conformations of ribose conformations of ribose deoxyribonucleotides of nucleic acids ribonucleotides of nucleic acids nucleotide and nucleic acid nomenclature. This is a continuation of the earlier slide with a name nucleotides.
Ppt in biochemistry free download from slideshare for students. Nucleotides and nucleic acids nucleotides bases ribose nucleotides polymerise nucleotides nucleotides as energy carriers structure of dna. Ppt chapter 28 nucleosides, nucleotides, and nucleic acids powerpoint presentation free to download id. Free dna powerpoint template free powerpoint templates.
Biochemistry ppt presentations download easybiologyclass. Nucleic acids are polymers that consist of nucleotide residues. A slide detailing how oligonucleotidess are synthesized with references too. The amino group nh 2 is basic while the carboxyl group cooh is acidic in nature. Molecular basis for the singlenucleotide precision of. Nucleotides are the components that made up nucleic acids. There are three major obstacles to the analysis of the nucleotide sequence in a dna molecule starting from a known location in the dna molecule.
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